INNOVATIONS IN BIOENGINEERED HEART VALVES: A FUTURE ALTERNATIVE TO MECHANICAL AND BIOPROSTHETIC VALVES
Keywords:
Bioengineered heart valves, tissue engineering, regenerative medicine, mechanical valves, bioprosthetic valvesAbstract
Heart valve disease is a major health concern, with existing treatment options—mechanical and bioprosthetic valves—presenting significant limitations such as thrombosis risks, anticoagulation requirements, and limited durability. Bioengineered heart valves offer a revolutionary alternative by integrating tissue engineering, regenerative medicine, and advanced biomaterials. This article explores innovations in bioengineered heart valves, their advantages, challenges, and future prospects in cardiovascular medicine.
References
1. Dohmen, P. M., et al. (2020). Decellularized xenografts: Advancements in bioprosthetic heart valve technology. Journal of Cardiovascular Surgery, 61(4), 532-540.
2. Gaetani, R., et al. (2020). Advances in 3D bioprinting for cardiovascular applications. Advanced Healthcare Materials, 9(14), 2000248.
3. Hockaday, L. A., et al. (2021). 3D bioprinting and its application in tissue-engineered heart valves. Frontiers in Bioengineering and Biotechnology, 9, 735620.
4. Rippel, R. A., et al. (2021). The role of synthetic polymer scaffolds in cardiovascular tissue engineering. Acta Biomaterialia, 127, 50-64.
5. Ruff, N., et al. (2021). Overcoming regulatory challenges in bioengineered heart valve development. Tissue Engineering Part A, 27(1-2), 1-13.
6. Schaefermeier, P. R., et al. (2021). The future of heart valve tissue engineering: Current advancements and challenges. Journal of Biomedical Materials Research, 109(5), 891-905.
7. Weber, B., et al. (2022). Stem cell approaches in cardiovascular tissue engineering. Stem Cells International, 2022, 2436218.
8. Zhao, Y., et al. (2020). Tissue-engineered heart valves: Current trends and future directions. Circulation Research, 127(2), 209-222.
9. Aslam, I. & Jiyanboyevich, Y.S. (2023). 'The common problem of international students and its solution and unexpected challenges of working with foreign teacher', Internationalization of Medical Education: Experience, Problems, Prospects, 66.
10. Jiyanboyevich, Y.S., Aslam, I. & Soatboyevich, J.N. (2024). 'Failure of the heart determination proteomic profiling related to patients who are elderly', Research Focus, 3(1), pp. 198-203.
11. Nodirovna, A.R., Maksudovna, M.M., Aslam, I. & Ergashboevna, A.Z. (2024). 'Evaluating novel anticoagulant and antiplatelet drugs for thromboembolic illness prevention and treatment', International Journal of Alternative and Contemporary Therapy, 2(5), pp. 135-141.
12. Shahzoda, K., Aslam, I., Ashraf, A., Ergashboevna, A.Z. & Ergashboevna, E.M. (2024). 'Advancements in surgical techniques: A comprehensive review', Ta'limda raqamli texnologiyalarni tadbiq etishning zamonaviy tendensiyalari va rivojlanish omillari, 31(2), pp. 139-149.
13. Aslam, I. & Jiyanboyevich, Y.S. (2023). 'The common problem of international students and its solution and unexpected challenges of working with foreign teacher', Internationalization of Medical Education: Experience, Problems, Prospects, 66.
14. Nodirovna, A.R., Maksudovna, M.M., Aslam, I. & Ergashboevna, A.Z. (2024). 'Evaluating novel anticoagulant and antiplatelet drugs for thromboembolic illness prevention and treatment', International Journal of Alternative and Contemporary Therapy, 2(5), pp. 135-141.
15. Aslam, I., Jiyanboyevich, Y.S. & Rajabboevna, A.R. (2023). 'Apixaban vs Rivaroxaban blood thinner use reduced stroke and clot risk in patients with heart disease and arrhythmia', Rivista Italiana di Filosofia Analitica Junior, 14(2), pp. 883-889.
16. Aslam, I., Jiyanboyevich, Y.S. & Rajabboevna, A.R. (2023). 'Apixaban vs Rivaroxaban blood thinner use reduced stroke and clot risk in patients with heart disease and arrhythmia', Rivista Italiana di Filosofia Analitica Junior, 14(2), pp. 883-889.
17. Jiyanboyevich, Y.S., Aslam, I., Ravshanovna, M.U., Azamatovna, F.G. & Murodovna, J.D. (2021). 'Ventricular arrhythmias with congenital heart disease causing sudden death', NVEO-Natural Volatiles & Essential Oils Journal, pp. 2055-2063.
Published
Issue
Section
License
Copyright (c) 2024 S.J. Yuldashev, Dr. Aslam Imran (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
All Rights Reserved.