7-ALMASHINGAN-2,3-DIGIDROPIRROLO[2,1-b]XINAZOLIN-9-ON HOSILALARINING SINTEZI
Keywords:
saraton, xinazolin, organoboronik kislotalar, pirralidon-2, toluol, seziy karbonatAbstract
7-almashingan-2,3-digidropirrolo[2,1-b]xinazolin-9(1H)-onning yangi hosilalarini sintez qilish uchun Suzuki-Miyaura usulidan foydalanildi. 7-bromo-2,3-digidropirrolo[2,1-b]xinazolin-9(1H)-onga halqada bir, ikki, va uch o‘rinbosar tutgan organoboronik kislotalar, Cs2CO3 hamda Pd(PPh3)4 katalizatorini toluol/suv(3:1) ishtirokida ta’sir ettirildi. Natijada 7-aril-2,3-digidropirrolo[2,1-b]xinazolin-9(1H)-onlarning yangi hosilalari sintez qilindi.
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